Intractable depression that doesn’t go away

Intractable depression (it can be found in Google and can happen to the best of us) is a real medical condition, most common causes being disability, chronic physical illness, health conditions, grief, loss and any event or condition that cannot be changed, relieved or leaves an imprint on one’s life. It might not can be cured or fixed but it can be treated by managing with the event or condition that can’t be changed and overcoming the negative imprint that has been left. It will always be a struggle for sufferers but can be treated and managed so that they can overcome in life. Unfortunately it can end in death but that is far less likely with proper treatment, if it comes soon enough.
The most devastating effect is it can impair the sufferers ability to care for their family or their ability to work or have a career, even with the best of care. The best solution is when the sufferer can accept their limitations and so get the help, support and resources they need to take the most positive direction they can in life.